Your cart Items: 0
  • Contact Us For Prices from India

  • For order Just Make A Request

  • Exporters Of Generic Medicines

Buy Generic Velcade (Bortezomib) » Bortenat »
product image

Generic Velcade

Bortezomib
(lyophilizate / 1 / 3.5mg)
Manufacturing: Natco
Indian brand: Bortenat
Shipping time: 7 - 14 days

Add to Cart 3.5mg
product image

Generic Velcade

Bortezomib
(lyophilizate / 1 / 2mg)
Manufacturing: Natco
Indian brand: Bortenat
Shipping time: 7 - 14 days

Add to Cart 2mg



















Description

Pharmacological action - an antineoplastic. Reversibly inhibits the chymotrypsin-like activity of the proteasome 26S. Proteasome 26S - large protein complex that catalyzes the cleavage of essential proteins and regulate their intracellular concentrations. So-called "ubiquitin-proteasome pathway" plays an important role in regulating the level of specific proteins, thereby maintaining homeostasis in mammalian cells. By inhibiting the action of chymotrypsin-like proteasome 26S, bortezomib causes inhibition of proteolysis, leading to a complex signaling cascade inside the cells, disruption of normal cell homeostasis and possibly apoptosis. Experiments have demonstrated that bortezomib is cytotoxic to a large number of tumor cell types in vitro. It also inhibits the growth of tumors in non-clinical in vivo tumor models, including multiple myeloma.