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Buy Generic Valtrex (Valacyclovir) |

US Brand: Valtrex
Indian (Generic) Brand: Valcivir
Manufacturing: Cipla
Active Substance: Valacyclovir
Dosage: 500mg / 1000mg
Form release: Blister 3 tablets
Order: through enquiry form
Shipping time: 9 – 14 days








Description

Antiviral nucleoside analogues group. Valaciclovir is the L-valine ester of acyclovir and is thus, a prodrug.

After absorption into the blood valacyclovir almost completely converted to acyclovir under the influence of hepatic enzyme valacyclovir hydrolase. Acyclovir, valaciclovir formed from, in turn, penetrates the virus-infected cells, where under the influence of a viral enzyme thymidine monophosphate is converted into, then, influenced by cellular kinases - to active diphosphate and triphosphate. Acyclovir triphosphate inhibits DNA polymerase and thus gives DNA replication of the virus. In addition, viral DNA replication breach may result from incorporation of acyclovir into its structure. Thus, the high selectivity of valaciclovir in respect of tissue affected by a virus, because I stage chain phosphorylation reactions mediated by enzymes produced by the virus.

It is active against Herpes simplex virus types 1 and 2, Varicella zoster, cytomegalovirus, Epstein-Barr virus, human herpes virus 6.